/* =========================================================================
   pages.css — inner content pages (AMR, Journey, How it works, Clinical data)
   ========================================================================= */

/* ---------- Campaign banner ---------- */
.page-banner {
  background: #0f1a33;
  line-height: 0;
}
.page-banner img {
  width: 100%;
  aspect-ratio: 2400 / 475;
  object-fit: cover;
}
@media (max-width: 768px) {
  .page-banner img { aspect-ratio: 1000 / 625; }
}

/* ---------- Breadcrumb ---------- */
.crumbs {
  padding-top: 22px;
  font-size: 13.5px;
  color: var(--ink-soft);
}
.crumbs ol { display: flex; flex-wrap: wrap; gap: 6px; margin: 0; padding: 0; list-style: none; }
.crumbs li + li::before { content: "/"; margin-right: 6px; color: var(--rule); }
.crumbs a { color: var(--ink-soft); text-decoration: none; }
.crumbs a:hover { color: var(--plum); text-decoration: underline; }

/* ---------- Page head ---------- */
.page-head { padding-block: 28px clamp(36px, 5vw, 56px); }
.page-head h1 {
  max-width: 24ch;
  margin: 0 0 16px;
  color: var(--plum);
  font-weight: 800;
  font-size: clamp(30px, 4vw, 48px);
  line-height: 1.1;
  letter-spacing: -.01em;
}
.page-head .lead {
  max-width: 68ch;
  margin: 0;
  font-size: clamp(17px, 1.5vw, 19px);
  line-height: 1.6;
  color: var(--ink);
}
#fn-only{padding-top: 20px;}

/* ---------- Section rhythm ---------- */
.section { padding-block: clamp(48px, 7vw, 88px); }
.section--tight { padding-top: 0; }
.section--mist { background: var(--mist); }
.section--plum { background: var(--plum); color: var(--white); }
.section--plum :focus-visible { outline-color: var(--white); }

.section h2 {
  max-width: 30ch;
  margin: 0 0 14px;
  color: var(--plum);
  font-weight: 800;
  font-size: clamp(24px, 2.8vw, 34px);
  line-height: 1.15;
}
.section--plum h2 { color: var(--white); }
.section h3 {
  margin: 0 0 10px;
  color: var(--aubergine);
  font-weight: 800;
  font-size: 19px;
  line-height: 1.3;
}
.section--plum h3 { color: var(--white); }
.section .intro { max-width: 68ch; margin: 0 0 clamp(28px, 4vw, 44px); font-size: 17px; }
.section--plum .intro { color: rgba(255,255,255,.88); }

.prose { max-width: 70ch; }
.prose p { margin: 0 0 18px; font-size: 17px; line-height: 1.75; }
.prose p:first-child { font-size: 19px; font-weight: 600; color: var(--aubergine); line-height: 1.6; }

/* ---------- Big numbers ---------- */
.stat-groups {
  display: grid;
  grid-template-columns: 1fr 1fr;
  gap: clamp(28px, 5vw, 64px);
}
.stat-group h3 {
  padding-bottom: 12px;
  margin-bottom: 8px;
  border-bottom: 2px solid var(--plum);
  color: var(--plum);
  font-weight: 600;
  font-size: 16px;
  letter-spacing: .02em;
}
.section--plum .stat-group h3 { color: var(--white); border-bottom-color: rgba(255,255,255,.6); }
.stat {
  display: grid;
  grid-template-columns: minmax(150px, auto) 1fr;
  align-items: baseline;
  gap: 18px;
  padding-block: 18px;
  border-bottom: 1px solid var(--rule);
}
.section--plum .stat { border-bottom-color: rgba(255,255,255,.25); }
.stat__num {
  margin: 0;
  color: var(--plum);
  font-weight: 800;
  font-size: clamp(38px, 4.4vw, 56px);
  line-height: 1;
  letter-spacing: -.02em;
  font-variant-numeric: tabular-nums;
}
.section--plum .stat__num { color: var(--white); }
.stat__text { margin: 0; font-size: 16px; line-height: 1.5; }
.section--plum .stat__text { color: rgba(255,255,255,.9); }

.stat-row {
  display: grid;
  grid-template-columns: repeat(3, 1fr);
  margin: 0; padding: 0; list-style: none;
}
.stat-row li { padding: 4px clamp(18px, 3vw, 36px); }
.stat-row li:first-child { padding-left: 0; }
.stat-row li + li { border-left: 1px solid var(--rule); }
.stat-row .stat__num { margin-bottom: 10px; }

@media (max-width: 860px) {
  .stat-groups { grid-template-columns: 1fr; }
  .stat-row { grid-template-columns: 1fr; }
  .stat-row li, .stat-row li:first-child { padding: 18px 0; }
  .stat-row li + li { border-left: 0; border-top: 1px solid var(--rule); }
}
@media (max-width: 480px) {
  .stat { grid-template-columns: 1fr; gap: 8px; }
}

/* ---------- Note / callout ---------- */
.note {
  max-width: 76ch;
  margin: clamp(24px, 3vw, 36px) 0 0;
  padding: 16px 20px;
  border-left: 4px solid var(--plum);
  background: var(--mist);
  border-radius: 0 var(--radius) var(--radius) 0;
  font-size: 15.5px;
}
.section--mist .note { background: var(--white); }
.note--important { font-weight: 600; }

.callout {
  display: grid;
  grid-template-columns: minmax(0, 1fr) minmax(0, 1.4fr);
  gap: clamp(24px, 5vw, 72px);
  align-items: start;
}
.callout h2 { margin: 0; }
.callout p { margin: 0; font-size: 18px; line-height: 1.65; }
@media (max-width: 860px) { .callout { grid-template-columns: 1fr; } }

/* ---------- Data tables ---------- */
.table-scroll {
  position: relative;   /* contains the screen-reader labels inside the table so they cannot widen the page */
  width: 100%;
  overflow-x: auto;
  -webkit-overflow-scrolling: touch;
  border: 1px solid var(--rule);
  border-radius: var(--radius);
  background: var(--white);
}
.table-scroll:focus-visible { outline-offset: 2px; }
.data-table {
  width: 100%;
  border-collapse: collapse;
  font-size: 15.5px;
  line-height: 1.4;
  font-variant-numeric: tabular-nums;
}
.data-table caption {
  padding: 16px 20px;
  text-align: left;
  color: var(--aubergine);
  font-weight: 800;
  font-size: 16px;
  border-bottom: 1px solid var(--rule);
}
.data-table th, .data-table td {
  padding: 14px 18px;
  text-align: left;
  border-bottom: 1px solid var(--rule);
  vertical-align: middle;
}
.data-table thead th {
  background: var(--plum);
  color: var(--white);
  font-weight: 600;
  font-size: 14.5px;
  vertical-align: bottom;
}
.data-table tbody th { font-weight: 600; color: var(--aubergine); }
.data-table tbody tr:last-child > * { border-bottom: 0; }
.data-table .num { text-align: center; white-space: nowrap; }
.data-table thead .num { white-space: normal; }
.spectrum-table { font-size: 14.5px; }
.spectrum-table th, .spectrum-table td { padding: 12px 12px; }
.spectrum-table thead th { font-size: 13.5px; }
.spectrum-table tbody td:nth-child(2), .spectrum-table tbody tr > td:first-child { min-width: 150px; }
.data-table thead .col-z { background: var(--plum-deep); }
.data-table tbody .col-z { background: var(--mist); font-weight: 600; color: var(--plum); }

/* Overflow cue — pages.js wraps each .table-scroll and toggles .has-more */
.table-wrap { position: relative; }
.table-wrap::after {
  content: "";
  position: absolute;
  top: 1px; right: 1px; bottom: 1px;
  width: 44px;
  border-radius: 0 var(--radius) var(--radius) 0;
  background: linear-gradient(90deg, rgba(255,255,255,0), rgba(255,255,255,.95));
  pointer-events: none;
  opacity: 0;
  transition: opacity .2s ease;
}
.table-wrap.has-more::after { opacity: 1; }
.table-hint {
  display: flex; align-items: center; gap: 8px;
  margin: 10px 0 0; font-size: 13.5px; color: var(--ink-soft);
}
.table-hint svg { width: 16px; height: 16px; color: var(--plum); }
.table-hint[hidden] { display: none; }

@media (max-width: 640px) {
  .data-table { font-size: 14px; }
  .data-table th, .data-table td { padding: 11px 10px; }
  .data-table caption { padding: 14px 12px; font-size: 15px; }
}

.footnotes {
  max-width: 90ch;
  margin: 14px 0 0;
  padding: 0;
  list-style: none;
  font-size: 13.5px;
  line-height: 1.6;
  color: var(--ink-soft);
}
.footnotes li { margin-bottom: 4px; }
.footnotes sup { font-size: .8em; margin-right: 2px; }

/* Spectrum marks */
.mark { display: inline-grid; place-items: center; width: 28px; height: 28px; border-radius: 50%; }
.mark svg { width: 14px; height: 14px; }
.mark--yes { background: var(--plum); color: var(--white); }
.mark--no { background: #fbe9ea; color: #b42330; }
.mark--var { background: #eee8f0; color: var(--ink); font-weight: 800; font-size: 17px; line-height: 1; }
.spectrum-table td.num { text-align: center; }
.spectrum-table tbody th[rowspan] { vertical-align: top; }
.legend {
  display: flex; flex-wrap: wrap; gap: 10px 28px;
  margin: 18px 0 0; padding: 0; list-style: none;
  font-size: 14.5px;
}
.legend li { display: flex; align-items: center; gap: 10px; }

/* ---------- Video ---------- */
.video-frame {
  position: relative;
  max-width: 1040px;
  aspect-ratio: 16 / 9;
  background: var(--aubergine);
  border-radius: var(--radius);
  overflow: hidden;
  box-shadow: 0 24px 60px -30px rgba(37,16,44,.6);
}
.video-frame video { width: 100%; height: 100%; object-fit: cover; background: var(--aubergine); }
.video-caption { max-width: 1040px; margin: 12px 0 0; font-size: 14px; color: var(--ink-soft); }

/* ---------- Comparison bars (efficacy) ---------- */
.bars { display: grid; gap: 22px; max-width: 880px; margin: 0; padding: 0; list-style: none; }
.bar__label {
  display: flex; justify-content: space-between; align-items: baseline; gap: 16px;
  margin-bottom: 8px;
}
.bar__name { font-weight: 600; font-size: 16px; }
.bar__value { font-weight: 800; font-size: clamp(28px, 3.2vw, 40px); line-height: 1; color: var(--plum); font-variant-numeric: tabular-nums; }
.bar__value small { font-weight: 400; font-size: 14px; color: var(--ink-soft); margin-left: 6px; }
.bar__track { height: 22px; background: var(--mist); border-radius: 999px; overflow: hidden; }
.bar__fill {
  height: 100%;
  width: var(--w);
  background: var(--plum);
  border-radius: 999px;
  transform-origin: left;
}
.bar--comparator .bar__value { color: var(--ink-soft); }
.bar--comparator .bar__fill { background: #b9a9bf; }
.js .bars:not(.is-in) .bar__fill { transform: scaleX(0); }
.bars.is-in .bar__fill { transform: scaleX(1); transition: transform 1.2s cubic-bezier(.2,.8,.2,1); }
.bar--comparator .bar__fill { transition-delay: .15s; }

.diff {
  display: inline-block;
  margin: 26px 0 0;
  padding: 12px 20px;
  border: 2px solid var(--plum);
  border-radius: var(--radius);
  font-size: 17px;
}
.diff strong { color: var(--plum); font-weight: 800; }

/* ---------- Trial design ---------- */
.arms {
  display: grid;
  grid-template-columns: 1fr auto 1fr;
  align-items: stretch;
  gap: 20px;
  max-width: 880px;
  margin: 0 0 32px;
}
.arm {
  padding: 22px 24px;
  border: 1px solid var(--rule);
  border-top: 4px solid var(--plum);
  border-radius: var(--radius);
  background: var(--white);
}
.arm--comparator { border-top-color: #b9a9bf; }
.arm h3 { margin: 0 0 6px; }
.arm p { margin: 0; font-size: 15.5px; }
.arm__n { margin-top: 10px !important; color: var(--ink-soft); font-size: 14px !important; }
.arms__or { align-self: center; font-weight: 600; color: var(--ink-soft); }
@media (max-width: 640px) {
  .arms { grid-template-columns: 1fr; }
  .arms__or { justify-self: center; }
}

/* ---------- Definition list with checks ---------- */
.checks { display: grid; gap: 14px; max-width: 80ch; margin: 24px 0 0; padding: 0; list-style: none; }
.checks li { display: grid; grid-template-columns: 22px 1fr; gap: 12px; font-size: 15.5px; }
.checks svg { width: 20px; height: 20px; margin-top: 3px; color: var(--plum); }

/* ---------- Warnings (safety page) ---------- */
.warn-grid {
  display: grid;
  grid-template-columns: repeat(3, 1fr);
  margin: 0; padding: 0; list-style: none;
}
.warn-grid > li { padding: 4px clamp(18px, 2.6vw, 32px) 4px; }
.warn-grid > li:first-child { padding-left: 0; }
.warn-grid > li + li { border-left: 1px solid var(--rule); }
.warn-grid p, .warn-grid li li { font-size: 15.5px; line-height: 1.6; }
.warn-grid p { margin: 0 0 12px; }
.warn-grid ul { margin: 0 0 12px; padding-left: 1.1em; }
.warn-grid li li::marker { color: var(--plum); }

.warn-list { max-width: 900px; margin: 0; padding: 0; list-style: none; border-top: 1px solid var(--rule); }
.warn-list li {
  display: grid;
  grid-template-columns: minmax(180px, 280px) 1fr;
  gap: 24px;
  padding: 18px 0;
  border-bottom: 1px solid var(--rule);
}
.warn-list h3 { margin: 0; font-size: 16.5px; }
.warn-list p { margin: 0; font-size: 15.5px; }

@media (max-width: 900px) {
  .warn-grid { grid-template-columns: 1fr; }
  .warn-grid > li, .warn-grid > li:first-child { padding: 22px 0; }
  .warn-grid > li + li { border-left: 0; border-top: 1px solid var(--rule); }
  .warn-list li { grid-template-columns: 1fr; gap: 6px; }
}

/* ---------- Population split (safety) ---------- */
.split-n { display: flex; flex-wrap: wrap; gap: 16px 56px; margin: 0 0 18px; padding: 0; list-style: none; }
.split-n li { display: grid; gap: 4px; }
.split-n .stat__num { font-size: clamp(44px, 5vw, 64px); }
.split-n li:last-child .stat__num { color: var(--ink-soft); }
.split-n span { font-size: 15.5px; }

.two-col { display: grid; grid-template-columns: 1fr 1fr; gap: clamp(28px, 5vw, 64px); align-items: start; }
@media (max-width: 860px) { .two-col { grid-template-columns: 1fr; } }

.plain-list { margin: 0 0 14px; padding-left: 1.2em; }
.plain-list li { margin-bottom: 6px; }
.plain-list li::marker { color: var(--plum); }

/* ---------- Sitemap ---------- */
.sitemap-list { columns: 2 280px; column-gap: 56px; margin: 0; padding: 0; list-style: none; }
.sitemap-list > li { break-inside: avoid; margin-bottom: 28px; }
.sitemap-list > li > a, .sitemap-list > li > span { font-weight: 800; font-size: 18px; color: var(--aubergine); text-decoration: none; }
.sitemap-list > li > a:hover { color: var(--plum); text-decoration: underline; }
.sitemap-list ul { margin: 10px 0 0; padding: 0 0 0 16px; list-style: none; border-left: 2px solid var(--rule); }
.sitemap-list ul a { display: inline-block; padding: 5px 0; }

@media (prefers-reduced-motion: reduce) {
  .js .bars:not(.is-in) .bar__fill { transform: none; }
}

/* Stats placed inside a callout keep their own type scale */
.callout .stat__num { font-size: clamp(38px, 4.4vw, 56px); line-height: 1; }
.callout .stat__text { font-size: 16px; line-height: 1.5; }

/* ---------- Editor content (WordPress page.php: Privacy Policy, Terms…) ---------- */
.entry-content h2 { margin: 36px 0 12px; color: var(--plum); font-weight: 800; font-size: 24px; line-height: 1.2; }
.entry-content h3 { margin: 28px 0 10px; color: var(--aubergine); font-weight: 800; font-size: 19px; }
.entry-content p, .entry-content li { font-size: 17px; line-height: 1.75; }
.entry-content p:first-child { font-size: 17px; font-weight: 400; color: inherit; }
.entry-content ul, .entry-content ol { padding-left: 1.3em; margin: 0 0 18px; }
.entry-content li::marker { color: var(--plum); }
.entry-content img { border-radius: var(--radius); }
.entry-content table { width: 100%; border-collapse: collapse; margin: 0 0 24px; }
.entry-content th, .entry-content td { padding: 10px 12px; border-bottom: 1px solid var(--rule); text-align: left; }

/* =========================================================================
   9.24.26 CONTENT UPDATE — new components
   ========================================================================= */

/* Page titles: short uppercase H1 + optional larger headline */
.page-head h1 { max-width: none; text-transform: uppercase; letter-spacing: .02em; font-size: clamp(28px, 3.4vw, 42px); }
.page-headline {
  max-width: 34ch; margin: 0 0 16px;
  color: var(--aubergine); font-weight: 600; font-size: clamp(21px, 2.3vw, 28px); line-height: 1.3;
}
.page-head .lead strong { color: var(--aubergine); }

/* AMR: WHO "top 10" subhead-level callout */
.callout-sub {
  max-width: 44ch; margin: 4px 0 0; padding: 4px 0 4px 20px;
  border-left: 5px solid var(--plum);
  color: var(--plum); font-weight: 800; font-size: clamp(20px, 2.2vw, 27px); line-height: 1.3;
}
/* AMR: emphasized line in the plum band */
.emph-line { margin: 14px 0 0; font-weight: 600; font-size: clamp(19px, 1.9vw, 23px); line-height: 1.45; color: var(--white); }
.stack p { margin: 0 0 16px; font-size: 17px; line-height: 1.7; }
.stack .stack__lead { font-weight: 800; font-size: 20px; line-height: 1.45; color: var(--aubergine); }

/* Icon sections (Journey, MOA) */
.journey-intro { max-width: 70ch; margin: 0 0 40px; font-size: 19px; line-height: 1.65; font-weight: 600; color: var(--aubergine); }
.icon-secs { display: grid; gap: 0; margin: 0; padding: 0; list-style: none; max-width: 980px; border-top: 1px solid var(--rule); }
.icon-sec { display: grid; grid-template-columns: 72px 1fr; gap: 28px; padding: 32px 0; border-bottom: 1px solid var(--rule); }
.icon-sec h3 { margin: 4px 0 12px; font-size: 21px; }
.icon-sec p { margin: 0 0 14px; font-size: 17px; line-height: 1.7; max-width: 72ch; }
.icon-sec p:last-child { margin-bottom: 0; }
.icon-sec__ico { display: grid; place-items: center; width: 72px; height: 72px; border-radius: 50%; background: var(--mist); color: var(--plum); }
.icon-sec__ico svg { width: 34px; height: 34px; }
@media (max-width: 640px) {
  .icon-sec { grid-template-columns: 1fr; gap: 14px; }
  .icon-sec__ico { width: 56px; height: 56px; }
  .icon-sec__ico svg { width: 28px; height: 28px; }
}

/* Journey quote */
.quote { max-width: 900px; margin: 0; }
.quote blockquote { margin: 0; }
.quote blockquote p { margin: 0; font-weight: 600; font-size: clamp(21px, 2.4vw, 30px); line-height: 1.4; }
.quote figcaption { margin-top: 22px; padding-top: 16px; border-top: 1px solid rgba(255,255,255,.4); font-size: 15px; color: rgba(255,255,255,.85); }
.quote figcaption strong { display: block; color: var(--white); font-size: 17px; }

/* MOA intro */
.big-lead { margin: 0 0 16px; font-size: 20px; font-weight: 600; color: var(--aubergine); }
.combo { margin: 0; padding: 0; list-style: none; }
.combo li { padding: 16px 0 16px 20px; border-left: 4px solid var(--plum); margin-bottom: 12px; background: var(--mist); border-radius: 0 var(--radius) var(--radius) 0; font-size: 16.5px; padding-right: 16px; }
.combo strong { color: var(--plum); }
.diff-card { padding: 28px 30px; border-radius: 10px; background: var(--plum); color: var(--white); }
.diff-card h2 { color: var(--white) !important; margin: 0 0 10px !important; font-size: 24px !important; }
.diff-card p { margin: 0 0 14px; font-size: 17px; line-height: 1.55; }
.diff-card .plain-list li { font-weight: 600; }
.diff-card .plain-list li::marker { color: var(--white); }

/* Microbiology: organisms */
.org-cols { display: grid; grid-template-columns: 1fr 2fr; border: 1px solid var(--rule); border-radius: 10px; overflow: hidden; }
.org-col { padding: 26px 30px; }
.org-col h3 { margin: 0 0 14px; font-size: 14px; letter-spacing: .1em; text-transform: uppercase; color: var(--ink-soft); }
.org-col ul { margin: 0; padding: 0; list-style: none; }
.org-col li { padding: 7px 0; border-bottom: 1px solid var(--rule); font-size: 16px; }
.org-col--clinical { background: var(--plum); color: var(--white); }
.org-col--clinical h3 { color: rgba(255,255,255,.85); }
.org-col--clinical li { border-bottom-color: rgba(255,255,255,.25); font-weight: 600; }
.org-col__two { columns: 2; column-gap: 32px; }
.org-col__two li { break-inside: avoid; }
@media (max-width: 760px) { .org-cols { grid-template-columns: 1fr; } .org-col__two { columns: 1; } }
.disclaimer { max-width: 90ch; margin: 18px 0 0; font-weight: 800; font-size: 15.5px; color: var(--aubergine); }
.mech-table tbody th { font-weight: 400; }
.mech-table tbody th.strong { font-weight: 600; }

/* Surveillance */
.study-design { max-width: 80ch; margin: 0 0 28px; font-size: 17px; line-height: 1.7; }
.h3-callout {
  max-width: 60ch; margin: 0 0 22px !important; padding: 18px 22px;
  background: var(--mist); border-left: 5px solid var(--plum); border-radius: 0 var(--radius) var(--radius) 0;
  color: var(--plum) !important; font-size: clamp(18px, 1.8vw, 21px) !important;
}
.surv-table { font-size: 14.5px; }
.surv-table tbody tr.row-group > * { background: #faf7fb; font-weight: 600; border-top: 2px solid var(--rule); }
.surv-table tbody tr.row-group .col-z { background: #efe4f3; }
.surv-table tbody tr.row-sub th { padding-left: 34px; font-weight: 400; }
.surv-table th[scope="row"] { min-width: 230px; }

/* Dosing: standard dosing first and most prominent */
.dose-std {
  display: grid; grid-template-columns: minmax(260px, 1fr) 2fr; overflow: hidden;
  border-radius: 12px; background: var(--plum); color: var(--white);
  box-shadow: 0 30px 70px -40px rgba(37,16,44,.55);
}
.dose-std__lead { padding: 32px 34px; background: var(--plum-deep); }
.dose-std__lead h2 { margin: 0 0 10px !important; color: rgba(255,255,255,.85) !important; font-size: 14px !important; letter-spacing: .12em; text-transform: uppercase; font-weight: 600 !important; }
.dose-std__dose { margin: 0; font-weight: 800; font-size: clamp(34px, 3.6vw, 46px); line-height: 1.05; }
.dose-std__comp { margin: 10px 0 0; font-size: 16px; opacity: .9; }
.dose-facts { display: grid; grid-template-columns: 1fr 1fr; margin: 0; padding: 12px 18px; list-style: none; align-content: center; }
.dose-facts li { display: grid; grid-template-columns: 52px 1fr; align-items: center; gap: 14px; padding: 16px 14px; font-weight: 600; font-size: 17px; line-height: 1.35; }
.dose-fact__ico { display: grid; place-items: center; width: 52px; height: 52px; border-radius: 50%; background: rgba(255,255,255,.14); }
.dose-fact__ico svg { width: 26px; height: 26px; }
.dose-std__sentence { max-width: 90ch; margin: 18px 0 0; font-size: 15px; color: var(--ink-soft); }
.renal-lead { max-width: 80ch; margin: 0 0 22px; font-size: 16.5px; }
.renal-lead strong { font-weight: 600; color: var(--aubergine); }
@media (max-width: 900px) {
  .dose-std { grid-template-columns: 1fr; }
  .dose-facts { grid-template-columns: 1fr; padding: 8px 10px; }
}

/* Efficacy: definitions with check icons vertically centered (MLR) */
.checks li { align-items: center; }
.checks svg { margin-top: 0; }
.checks p { margin: 0; }
.prose--plain p:first-child { font-size: 17px; font-weight: 400; color: inherit; }
.section h2.h2-wide { max-width: 44ch; }
.callout .emph-line { margin-top: 16px; }
.video-frame video { object-fit: contain; }


/* AMR: "Without new treatments…" — visual emphasis requested by MLR */
.emph-line--highlight {
  margin: 24px 0 0;
  padding: 18px 22px;
  border-left: 6px solid var(--white);
  border-radius: 0 var(--radius) var(--radius) 0;
  background: rgba(255, 255, 255, .12);
  color: var(--white);
  font-weight: 800;
  font-size: clamp(20px, 2.2vw, 27px);
  line-height: 1.35;
  letter-spacing: -.005em;
}

/* =========================================================================
   MLR 10.8.26 additions
   ========================================================================= */
/* AMR: quote with attribution */
.pull-quote { margin: 4px 0 0; padding: 18px 22px; border-left: 4px solid var(--plum); background: var(--white); border-radius: 0 var(--radius) var(--radius) 0; }
.pull-quote blockquote { margin: 0; }
.pull-quote blockquote p { margin: 0; font-style: italic; font-size: 17px; line-height: 1.7; }
.pull-quote figcaption { margin-top: 10px; font-weight: 600; font-size: 14.5px; color: var(--ink-soft); }
.pull-quote cite { font-style: italic; }

/* Journey: jump link to indication + footnote */
.see-ind { font-weight: 600; }
.fn-ref { margin-left: 1px; font-weight: 700; text-decoration: none; vertical-align: super; font-size: .75em; line-height: 0; }
.page-footnote { margin: 0 0 clamp(32px, 4vw, 48px); }

/* Microbiology: disclaimer next to the headline */
.disclaimer--head { margin-top: 4px; padding: 50px 16px; border: 1.5px solid var(--plum); border-radius: var(--radius); max-width: 60ch; }
.micr-top{display: flex;}
/* Clinical efficacy: indication statement under the headline */
.ind-box { max-width: 80ch; margin: 6px 0 22px; padding: 18px 22px; background: var(--mist); border-left: 4px solid var(--plum); border-radius: 0 var(--radius) var(--radius) 0; }
.ind-box h2 { margin: 0 0 8px; color: #000; font-weight: 800; font-size: 15px; letter-spacing: .03em; text-transform: uppercase; }
.ind-box h3 { margin: 10px 0 4px; color: #000; font-weight: 700; font-size: 15.5px; }
.ind-box p { margin: 0; font-size: 15.5px; line-height: 1.65; }

/* Surveillance: interim campaign-neutral banner */
.page-banner--plain { background: #efe8f6; }

/* Legal pages */
.legal-updated { margin: 0; color: var(--ink-soft); font-size: 14.5px; }
.legal { max-width: 78ch; }
.legal h2 { margin: 34px 0 10px; color: var(--plum); font-weight: 800; font-size: 21px; line-height: 1.25; }
.legal h2:first-child { margin-top: 0; }
.legal p, .legal li { font-size: 16.5px; line-height: 1.75; }
.legal p { margin: 0 0 14px; }
.legal ul { margin: 0 0 14px; padding-left: 1.25em; }
.legal li { margin-bottom: 8px; }
.legal li::marker { color: var(--plum); }

@media (max-width: 600px) {
  .micr-top{display: block;}
}





/* ---------- MLR 10.8.26 PH2 ---------- */
/* Safety: all seven Warnings and Precautions in equal columns */
.warn-grid { row-gap: 40px; }
.warn-grid > li:nth-child(3n+1) { padding-left: 0; border-left: 0; }
.warn-grid ul.hang { list-style: none; padding-left: 0; }
.warn-grid ul.hang > li { position: relative; padding-left: 1.2em; }
.warn-grid ul.hang > li::before { content: "◦"; position: absolute; left: .1em; color: var(--plum); font-weight: 700; }
/* Pharmacovigilance: FDA reporting line */
.pv-fda { max-width: 960px; margin: 28px 0 0; font-size: 16px; }
@media (max-width: 900px) { .warn-grid { row-gap: 0; } }
/* Cookie Policy table */
.table-scroll:has(> .legal-table) { overflow-x: auto; margin: 0 0 1.2em; }
.legal-table { width: 100%; border-collapse: collapse; font-size: 14px; min-width: 520px; }
.legal-table th, .legal-table td { padding: 10px 12px; border: 1px solid var(--rule); text-align: left; vertical-align: top; }
.legal-table th { background: var(--mist); color: var(--aubergine); font-weight: 700; }

/* MLR 10.15.26: prominent in vitro disclaimer (Mechanism of Action) */
.disclaimer--box { margin-top: 22px; padding: 14px 18px; border: 1.5px solid var(--plum); border-radius: var(--radius); background: #fff; }